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SIAXI: Placebo-controlled, randomized, double-blind study of incobotulinumtoxinA for sialorrhea

OBJECTIVE: This pivotal phase III study, SIAXI, investigated the efficacy and safety of incobotulinumtoxinA for the treatment of chronic sialorrhea due to Parkinson disease (PD), atypical parkinsonism, stroke, or traumatic brain injury (TBI). METHODS: Adult patients with PD (70.7%), atypical parkins...

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Detalles Bibliográficos
Autores principales: Jost, Wolfgang H., Friedman, Andrzej, Michel, Olaf, Oehlwein, Christian, Slawek, Jaroslaw, Bogucki, Andrzej, Ochudlo, Stanislaw, Banach, Marta, Pagan, Fernando, Flatau-Baqué, Birgit, Csikós, János, Cairney, Claire J., Blitzer, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511076/
https://www.ncbi.nlm.nih.gov/pubmed/30918101
http://dx.doi.org/10.1212/WNL.0000000000007368