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Relative effects of LDL-C on ischemic stroke and coronary disease: A Mendelian randomization study

OBJECTIVE: To examine the causal relevance of lifelong differences in low-density lipoprotein cholesterol (LDL-C) for ischemic stroke (IS) relative to that for coronary heart disease (CHD) using a Mendelian randomization approach. METHODS: We undertook a 2-sample Mendelian randomization, based on su...

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Detalles Bibliográficos
Autores principales: Valdes-Marquez, Elsa, Parish, Sarah, Clarke, Robert, Stari, Traiani, Worrall, Bradford B., Hopewell, Jemma C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511103/
https://www.ncbi.nlm.nih.gov/pubmed/30787162
http://dx.doi.org/10.1212/WNL.0000000000007091