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Apathy is associated with large-scale white matter network disruption in small vessel disease

OBJECTIVE: To investigate whether white matter network disruption underlies the pathogenesis of apathy, but not depression, in cerebral small vessel disease (SVD). METHODS: Three hundred thirty-one patients with SVD from the Radboud University Nijmegen Diffusion Tensor and Magnetic Resonance Cohort...

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Detalles Bibliográficos
Autores principales: Tay, Jonathan, Tuladhar, Anil M., Hollocks, Matthew J., Brookes, Rebecca L., Tozer, Daniel J., Barrick, Thomas R., Husain, Masud, de Leeuw, Frank-Erik, Markus, Hugh S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511108/
https://www.ncbi.nlm.nih.gov/pubmed/30737341
http://dx.doi.org/10.1212/WNL.0000000000007095