Weighting sequence variants based on their annotation increases the power of genome-wide association studies in dairy cattle

BACKGROUND: Genome-wide association studies (GWAS) are widely used to identify regions of the genome that harbor genetic determinants of quantitative traits. However, the multiple-testing burden from scanning tens of millions of whole-genome sequence variants reduces the power to identify associated...

Descripción completa

Detalles Bibliográficos
Autores principales: Cai, Zexi, Guldbrandtsen, Bernt, Lund, Mogens Sandø, Sahana, Goutam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511139/
https://www.ncbi.nlm.nih.gov/pubmed/31077144
http://dx.doi.org/10.1186/s12711-019-0463-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511139/
https://www.ncbi.nlm.nih.gov/pubmed/31077144
http://dx.doi.org/10.1186/s12711-019-0463-9

Ejemplares similares