Peripheral administration of human recombinant ApoJ/clusterin modulates brain beta-amyloid levels in APP23 mice

BACKGROUND: ApoJ/clusterin is a multifunctional protein highly expressed in the brain. The implication of ApoJ in β-amyloid (Aβ) fibrillization and clearance in the context of Alzheimer’s disease has been widely studied, although the source and concentration of ApoJ that promotes or inhibits Aβ cere...

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Detalles Bibliográficos
Autores principales: de Retana, Sofía Fernández, Marazuela, Paula, Solé, Montse, Colell, Guillem, Bonaterra, Anna, Sánchez-Quesada, Jose Luis, Montaner, Joan, Maspoch, Daniel, Cano-Sarabia, Mary, Hernández-Guillamon, Mar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511153/
https://www.ncbi.nlm.nih.gov/pubmed/31077261
http://dx.doi.org/10.1186/s13195-019-0498-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511153/
https://www.ncbi.nlm.nih.gov/pubmed/31077261
http://dx.doi.org/10.1186/s13195-019-0498-8

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