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Peripheral administration of human recombinant ApoJ/clusterin modulates brain beta-amyloid levels in APP23 mice

BACKGROUND: ApoJ/clusterin is a multifunctional protein highly expressed in the brain. The implication of ApoJ in β-amyloid (Aβ) fibrillization and clearance in the context of Alzheimer’s disease has been widely studied, although the source and concentration of ApoJ that promotes or inhibits Aβ cere...

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Detalles Bibliográficos
Autores principales:	de Retana, Sofía Fernández, Marazuela, Paula, Solé, Montse, Colell, Guillem, Bonaterra, Anna, Sánchez-Quesada, Jose Luis, Montaner, Joan, Maspoch, Daniel, Cano-Sarabia, Mary, Hernández-Guillamon, Mar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511153/ https://www.ncbi.nlm.nih.gov/pubmed/31077261 http://dx.doi.org/10.1186/s13195-019-0498-8

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