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ZBTB12 DNA methylation is associated with coagulation- and inflammation-related blood cell parameters: findings from the Moli-family cohort

BACKGROUND: Zinc finger and BTB domain-containing protein 12 (ZBTB12) is a predicted transcription factor with potential role in hematopoietic development. Recent evidence linked low methylation level of ZBTB12 exon1 to myocardial infarction (MI) risk. However, the role of ZBTB12 in the pathogenesis...

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Detalles Bibliográficos
Autores principales: Noro, Fabrizia, Gianfagna, Francesco, Gialluisi, Alessandro, De Curtis, Amalia, Di Castelnuovo, Augusto, Napoleone, Emanuela, Cerletti, Chiara, Donati, Maria Benedetta, de Gaetano, Giovanni, Hoylaerts, Marc F., Iacoviello, Licia, Izzi, Benedetta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511189/
https://www.ncbi.nlm.nih.gov/pubmed/31077224
http://dx.doi.org/10.1186/s13148-019-0665-6