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HSP70 is required for the proper assembly of pericentriolar material and function of mitotic centrosomes

BACKGROUND: At the onset of mitosis, the centrosome expands and matures, acquiring enhanced activities for microtubule nucleation and assembly of a functional bipolar mitotic spindle. However, the mechanisms that regulate centrosome expansion and maturation are largely unknown. Previously, we demons...

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Detalles Bibliográficos
Autores principales: Fang, Chieh-Ting, Kuo, Hsiao-Hui, Hsu, Shao-Chun, Yih, Ling-Huei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511203/
https://www.ncbi.nlm.nih.gov/pubmed/31110557
http://dx.doi.org/10.1186/s13008-019-0047-7