Downregulation of MALAT1 alleviates saturated fatty acid-induced myocardial inflammatory injury via the miR-26a/HMGB1/TLR4/NF-κB axis

Purpose: The increased level of saturated fatty acids (SFAs) is found in patients with diabetes, obesity, and other metabolic disorders. SFAs can induce lipotoxic damage to cardiomyocytes, but the mechanism is unclear. The long noncoding RNA metastasis-associated lung adenocarcinoma transcript 1 (MA...

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Detalles Bibliográficos
Autores principales: Jia, Pengyu, Wu, Nan, Jia, Dalin, Sun, Yingxian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511247/
https://www.ncbi.nlm.nih.gov/pubmed/31123414
http://dx.doi.org/10.2147/DMSO.S203151

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511247/
https://www.ncbi.nlm.nih.gov/pubmed/31123414
http://dx.doi.org/10.2147/DMSO.S203151

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