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Targeting myeloid-derived suppressor cells in the treatment of hepatocellular carcinoma: current state and future perspectives

Systemic therapy for advanced hepatocellular carcinoma (HCC) has been focusing on overcoming tumor angiogenesis and immunosuppression. Myeloid-derived suppressor cells (MDSCs) promote both angiogenesis and immunosuppression in the tumor microenvironment (TME). Multiple clinical studies have demonstr...

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Detalles Bibliográficos
Autores principales: Lu, Li-Chun, Chang, Chun-Jung, Hsu, Chih-Hung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511249/
https://www.ncbi.nlm.nih.gov/pubmed/31123667
http://dx.doi.org/10.2147/JHC.S159693