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Partial Deletion of Tie2 Affects Microvascular Endothelial Responses to Critical Illness in A Vascular Bed and Organ-Specific Way

Tyrosine kinase receptor (Tie2) is mainly expressed by endothelial cells. In animal models mimicking critical illness, Tie2 levels in organs are temporarily reduced. Functional consequences of these reduced Tie2 levels on microvascular endothelial behavior are unknown. We investigated the effect of...

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Detalles Bibliográficos
Autores principales: Jongman, Rianne M., Zwiers, Peter J., van de Sluis, Bart, van der Laan, Marleen, Moser, Jill, Zijlstra, Jan G., Dekker, Daphne, Huijkman, Nicolette, Moorlag, Henk E., Popa, Eliane R., Molema, Grietje, van Meurs, Matijs
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511431/
https://www.ncbi.nlm.nih.gov/pubmed/30520765
http://dx.doi.org/10.1097/SHK.0000000000001226