Preliminary Studies of the Impact of CXCL12 on the Foreign Body Reaction to Pancreatic Islets Microencapsulated in Alginate in Nonhuman Primates

BACKGROUND. We previously demonstrated that the incorporation of the chemokine CXCL12 into alginate microbeads supported long-term survival of microencapsulated auto-, allo-, and xenogeneic islets in murine models of diabetes without systemic immune suppression. The purpose of this study was to test...

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Detalles Bibliográficos
Autores principales: Sremac, Marinko, Lei, Ji, Penson, Madeline F.E., Schuetz, Christian, Lakey, Jonathan R.T., Papas, Klearchos K., Varde, Pushkar S., Hering, Bernhard, de Vos, Paul, Brauns, Timothy, Markmann, James, Poznansky, Mark C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2019
Materias:
Pancreas and Islet Transplantation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511446/
https://www.ncbi.nlm.nih.gov/pubmed/31165082
http://dx.doi.org/10.1097/TXD.0000000000000890

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511446/
https://www.ncbi.nlm.nih.gov/pubmed/31165082
http://dx.doi.org/10.1097/TXD.0000000000000890

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