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Preliminary Studies of the Impact of CXCL12 on the Foreign Body Reaction to Pancreatic Islets Microencapsulated in Alginate in Nonhuman Primates
BACKGROUND. We previously demonstrated that the incorporation of the chemokine CXCL12 into alginate microbeads supported long-term survival of microencapsulated auto-, allo-, and xenogeneic islets in murine models of diabetes without systemic immune suppression. The purpose of this study was to test...
Autores principales: | Sremac, Marinko, Lei, Ji, Penson, Madeline F.E., Schuetz, Christian, Lakey, Jonathan R.T., Papas, Klearchos K., Varde, Pushkar S., Hering, Bernhard, de Vos, Paul, Brauns, Timothy, Markmann, James, Poznansky, Mark C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer Health
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511446/ https://www.ncbi.nlm.nih.gov/pubmed/31165082 http://dx.doi.org/10.1097/TXD.0000000000000890 |
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