ClampFISH detects individual nucleic-acid molecules using click chemistry based amplification

Methods for detecting single nucleic acids in cell and tissues, such as fluorescence in situ hybridization (FISH), are limited by relatively low signal intensity and non-specific probe binding. Here we present click-amplifying FISH (clampFISH), a method for fluorescence detection of nucleic acids th...

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Detalles Bibliográficos
Autores principales: Rouhanifard, Sara H., Mellis, Ian A., Dunagin, Margaret, Bayatpour, Sareh, Jiang, Connie L., Dardani, Ian, Symmons, Orsolya, Emert, Benjamin, Torre, Eduardo, Cote, Allison, Sullivan, Alessandra, Stamatoyannopoulos, John A., Raj, Arjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511493/
https://www.ncbi.nlm.nih.gov/pubmed/30418432
http://dx.doi.org/10.1038/nbt.4286

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511493/
https://www.ncbi.nlm.nih.gov/pubmed/30418432
http://dx.doi.org/10.1038/nbt.4286

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