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Conversion of staphylococcal pathogenicity islands to CRISPR-Cas9-based antibacterial drones that cure staph infections in mice
Staphylococcus aureus and other staphylococci continue to cause life-threatening infections in both hospital and community settings. They have become increasingly resistant to antibiotics, especially β-lactams and aminoglycosides, and their infections are now, in many cases, untreatable. Here, we pr...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511514/ https://www.ncbi.nlm.nih.gov/pubmed/30247487 http://dx.doi.org/10.1038/nbt.4203 |