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Generation of a CRISPR/Cas9-Based Vector Specific for Gene Manipulation in Leishmania major

BACKGROUND: Gene manipulation strategies including gene knockout and editing are becoming more sophisticated in terms of mechanism of action, efficacy and ease of use. In classical molecular methods of gene knockout, homologous arms are designed for induction of crossing over event in double strand...

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Detalles Bibliográficos
Autores principales: SALEHI SANGANI, Ghodratollah, JAJARMI, Vahid, KHAMESIPOUR, Ali, MAHMOUDI, Mahmoud, FATA, Abdolmajid, MOHEBALI, Mehdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tehran University of Medical Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511583/
https://www.ncbi.nlm.nih.gov/pubmed/31123471