Transient Down-Regulation of Nucleoside Transporter 3 Gene Expression as a Drug Target in Leishmania major Using Antisense RNA Technology

BACKGROUND: This study was aimed to silencing the Nucleoside transporter 3 (NT3) permease nucleobases involved in the salvage pathway of Leishmania in order to disrupt purine nucleotide uptake in the parasite and consequently, destruction of the parasite. METHODS: Overall, 502 bp fragment of the NT3...

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Detalles Bibliográficos
Autores principales: TOHIDI, Farideh, KAZEMI, Bahram, BANDEHPOUR, Mojgan, SHARIFI, Iraj, RABIEI, Mohammad Reza, SAEDI DEZAKI, Ebrahim, BABAEI, Zahra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tehran University of Medical Sciences 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511602/
https://www.ncbi.nlm.nih.gov/pubmed/31123475

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511602/
https://www.ncbi.nlm.nih.gov/pubmed/31123475

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