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Biclustering analysis of transcriptome big data identifies condition-specific microRNA targets

We present a novel approach to identify human microRNA (miRNA) regulatory modules (mRNA targets and relevant cell conditions) by biclustering a large collection of mRNA fold-change data for sequence-specific targets. Bicluster targets were assessed using validated messenger RNA (mRNA) targets and ex...

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Detalles Bibliográficos
Autores principales: Yoon, Sora, Nguyen, Hai C T, Jo, Woobeen, Kim, Jinhwan, Chi, Sang-Mun, Park, Jiyoung, Kim, Seon-Young, Nam, Dougu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511842/
https://www.ncbi.nlm.nih.gov/pubmed/30820547
http://dx.doi.org/10.1093/nar/gkz139