The RecQ helicase Sgs1 drives ATP-dependent disruption of Rad51 filaments

DNA helicases of the RecQ family are conserved among the three domains of life and play essential roles in genome maintenance. Mutations in several human RecQ helicases lead to diseases that are marked by cancer predisposition. The Saccharomyces cerevisiae RecQ helicase Sgs1 is orthologous to human...

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Detalles Bibliográficos
Autores principales: Crickard, J Brooks, Xue, Chaoyou, Wang, Weibin, Kwon, Youngho, Sung, Patrick, Greene, Eric C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511845/
https://www.ncbi.nlm.nih.gov/pubmed/30916344
http://dx.doi.org/10.1093/nar/gkz186

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511845/
https://www.ncbi.nlm.nih.gov/pubmed/30916344
http://dx.doi.org/10.1093/nar/gkz186

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