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A single-input binary counting module based on serine integrase site-specific recombination
A device that counts and records the number of events experienced by an individual cell could have many uses in experimental biology and biotechnology. Here, we report a DNA-based ‘latch’ that switches between two states upon each exposure to a repeated stimulus. The key component of the latch is a...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511857/ https://www.ncbi.nlm.nih.gov/pubmed/30957849 http://dx.doi.org/10.1093/nar/gkz245 |