Modulation of HIV-1 gene expression by binding of a ULM motif in the Rev protein to UHM-containing splicing factors

The HIV-1 protein Rev is essential for virus replication and ensures the expression of partially spliced and unspliced transcripts. We identified a ULM (UHM ligand motif) motif in the Arginine-Rich Motif (ARM) of the Rev protein. ULMs (UHM ligand motif) mediate protein interactions during spliceosom...

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Detalles Bibliográficos
Autores principales: Pabis, Marta, Corsini, Lorenzo, Vincendeau, Michelle, Tripsianes, Konstantinos, Gibson, Toby J, Brack-Werner, Ruth, Sattler, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511859/
https://www.ncbi.nlm.nih.gov/pubmed/30892606
http://dx.doi.org/10.1093/nar/gkz185

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511859/
https://www.ncbi.nlm.nih.gov/pubmed/30892606
http://dx.doi.org/10.1093/nar/gkz185

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