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Next-level riboswitch development—implementation of Capture-SELEX facilitates identification of a new synthetic riboswitch
The development of synthetic riboswitches has always been a challenge. Although a number of interesting proof-of-concept studies have been published, almost all of these were performed with the theophylline aptamer. There is no shortage of small molecule-binding aptamers; however, only a small fract...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511860/ https://www.ncbi.nlm.nih.gov/pubmed/30957848 http://dx.doi.org/10.1093/nar/gkz216 |