Cargando…

Translation termination depends on the sequential ribosomal entry of eRF1 and eRF3

Translation termination requires eRF1 and eRF3 for polypeptide- and tRNA-release on stop codons. Additionally, Dbp5/DDX19 and Rli1/ABCE1 are required; however, their function in this process is currently unknown. Using a combination of in vivo and in vitro experiments, we show that they regulate a s...

Descripción completa

Detalles Bibliográficos
Autores principales: Beißel, Christian, Neumann, Bettina, Uhse, Simon, Hampe, Irene, Karki, Prajwal, Krebber, Heike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511868/
https://www.ncbi.nlm.nih.gov/pubmed/30873535
http://dx.doi.org/10.1093/nar/gkz177