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Translation termination depends on the sequential ribosomal entry of eRF1 and eRF3

Translation termination requires eRF1 and eRF3 for polypeptide- and tRNA-release on stop codons. Additionally, Dbp5/DDX19 and Rli1/ABCE1 are required; however, their function in this process is currently unknown. Using a combination of in vivo and in vitro experiments, we show that they regulate a s...

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Detalles Bibliográficos
Autores principales:	Beißel, Christian, Neumann, Bettina, Uhse, Simon, Hampe, Irene, Karki, Prajwal, Krebber, Heike
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2019
Materias:	RNA and RNA-protein complexes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511868/ https://www.ncbi.nlm.nih.gov/pubmed/30873535 http://dx.doi.org/10.1093/nar/gkz177

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