Small extrachromosomal circular DNAs, microDNA, produce short regulatory RNAs that suppress gene expression independent of canonical promoters

Interest in extrachromosomal circular DNA (eccDNA) molecules has increased recently because of their widespread presence in normal cells across every species ranging from yeast to humans, their increased levels in cancer cells and their overlap with oncogenic and drug-resistant genes. However, the m...

Descripción completa

Detalles Bibliográficos
Autores principales: Paulsen, Teressa, Shibata, Yoshiyuki, Kumar, Pankaj, Dillon, Laura, Dutta, Anindya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511871/
https://www.ncbi.nlm.nih.gov/pubmed/30828735
http://dx.doi.org/10.1093/nar/gkz155

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511871/
https://www.ncbi.nlm.nih.gov/pubmed/30828735
http://dx.doi.org/10.1093/nar/gkz155

Ejemplares similares