Next-generation sequencing-guided identification and reconstruction of antibody CDR combinations from phage selection outputs

Next-generation sequencing (NGS) technologies have been employed in several phage display platforms for analyzing natural and synthetic antibody sequences and for identifying and reconstructing single-chain variable fragments (scFv) and antigen-binding fragments (Fab) not found by conventional ELISA...

Descripción completa

Detalles Bibliográficos
Autores principales: Barreto, Kris, Maruthachalam, Bharathikumar V, Hill, Wayne, Hogan, Daniel, Sutherland, Ashley R, Kusalik, Anthony, Fonge, Humphrey, DeCoteau, John F, Geyer, C Ronald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511873/
https://www.ncbi.nlm.nih.gov/pubmed/30854567
http://dx.doi.org/10.1093/nar/gkz131

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511873/
https://www.ncbi.nlm.nih.gov/pubmed/30854567
http://dx.doi.org/10.1093/nar/gkz131

Ejemplares similares