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Next-generation sequencing-guided identification and reconstruction of antibody CDR combinations from phage selection outputs

Next-generation sequencing (NGS) technologies have been employed in several phage display platforms for analyzing natural and synthetic antibody sequences and for identifying and reconstructing single-chain variable fragments (scFv) and antigen-binding fragments (Fab) not found by conventional ELISA...

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Detalles Bibliográficos
Autores principales:	Barreto, Kris, Maruthachalam, Bharathikumar V, Hill, Wayne, Hogan, Daniel, Sutherland, Ashley R, Kusalik, Anthony, Fonge, Humphrey, DeCoteau, John F, Geyer, C Ronald
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2019
Materias:	Methods Online
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511873/ https://www.ncbi.nlm.nih.gov/pubmed/30854567 http://dx.doi.org/10.1093/nar/gkz131

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