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Modulation of the helical properties of DNA: next-to-nearest neighbour effects and beyond

We used extensive molecular dynamics simulations to study the structural and dynamic properties of the central d(TpA) step in the highly polymorphic d(CpTpApG) tetranucleotide. Contrary to the assumption of the dinucleotide-model and its nearest neighbours (tetranucleotide-model), the properties of...

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Detalles Bibliográficos
Autores principales: Balaceanu, Alexandra, Buitrago, Diana, Walther, Jürgen, Hospital, Adam, Dans, Pablo D, Orozco, Modesto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511876/
https://www.ncbi.nlm.nih.gov/pubmed/30957854
http://dx.doi.org/10.1093/nar/gkz255