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Modulations of Histone Deacetylase 2 Offer a Protective Effect through the Mitochondrial Apoptosis Pathway in Acute Liver Failure

The purpose of this study was to investigate the modulation of histone deacetylase 2 (HDAC2) on mitochondrial apoptosis in acute liver failure (ALF). The cellular model was established with LO2 cells stimulated by tumor necrosis factor alpha (TNF-α)/D-galactosamine (D-gal). Rats were administrated b...

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Detalles Bibliográficos
Autores principales: Wang, Yao, Yang, Fan, Jiao, Fang-Zhou, Chen, Qian, Zhang, Wen-Bin, Wang, Lu-Wen, Gong, Zuo-Jiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6512023/
https://www.ncbi.nlm.nih.gov/pubmed/31183000
http://dx.doi.org/10.1155/2019/8173016