Triptolide Inhibits Preformed Fibril-Induced Microglial Activation by Targeting the MicroRNA155-5p/SHIP1 Pathway

Evidence suggests that various forms of α-synuclein- (αSyn-) mediated microglial activation are associated with the progression of Parkinson's disease. MicroRNA-155-5p (miR155-5p) is one of the most important microRNAs and enables a robust inflammatory response. Triptolide (T10) is a natural an...

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Detalles Bibliográficos
Autores principales: Feng, Yang, Zheng, Chuyun, Zhang, Yajun, Xing, Changyang, Cai, Wenbin, Li, Ruru, Chen, Jianzong, Duan, Yunyou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6512043/
https://www.ncbi.nlm.nih.gov/pubmed/31182996
http://dx.doi.org/10.1155/2019/6527638

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6512043/
https://www.ncbi.nlm.nih.gov/pubmed/31182996
http://dx.doi.org/10.1155/2019/6527638

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