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Novel Role of Carbon Monoxide in Improving Neurological Outcome After Cardiac Arrest in Aged Rats: Involvement of Inducing Mitochondrial Autophagy

BACKGROUND: Dysfunctional mitochondria are associated with neurological injury after cardiac arrest (CA). Although carbon monoxide (CO) has shown various potential therapeutic effects in preclinical tissue injury models, its mechanism of action in CA remains unclear. We sought to investigate the eff...

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Detalles Bibliográficos
Autores principales: Wu, Jun, Li, Yi, Yang, Peng, Huang, Yaping, Lu, Shiqi, Xu, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6512094/
https://www.ncbi.nlm.nih.gov/pubmed/31030597
http://dx.doi.org/10.1161/JAHA.118.011851