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Chromatin Conformation Links Putative Enhancers in Intracranial Aneurysm–Associated Regions to Potential Candidate Genes
BACKGROUND: We previously showed that intracranial aneurysm (IA)–associated single‐nucleotide polymorphisms are enriched in promoters and putative enhancers identified in the human circle of Willis, on which IAs develop, suggesting a role for promoters and enhancers in IAs. We further investigated t...
Autores principales: | Laarman, Melanie D., Geeven, Geert, Barnett, Phil, Rinkel, Gabriël J. E., de Laat, Wouter, Ruigrok, Ynte M., Bakkers, Jeroen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6512097/ https://www.ncbi.nlm.nih.gov/pubmed/30994044 http://dx.doi.org/10.1161/JAHA.118.011201 |
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