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Arhgef1 Plays a Vital Role in Platelet Function and Thrombogenesis

BACKGROUND: Platelets are the cellular mediators of hemostasis and thrombosis, and their function is regulated by a number of molecular mediators, such as small GTPases. These small GTPases are themselves regulated by guanine nucleotide exchange factors such as Arhgefs, several of which are found in...

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Detalles Bibliográficos
Autores principales: Qasim, Hanan, Karim, Zubair A., Hernandez, Keziah R., Lozano, Dante, Khasawneh, Fadi T., Alshbool, Fatima Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6512111/
https://www.ncbi.nlm.nih.gov/pubmed/30994039
http://dx.doi.org/10.1161/JAHA.118.011712