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Arterial Stiffness Due to Carotid Calcification Disrupts Cerebral Blood Flow Regulation and Leads to Cognitive Deficits

BACKGROUND: Arterial stiffness is associated with cognitive decline and dementia; however, the precise mechanisms by which it affects the brain remain unclear. METHODS AND RESULTS: Using a mouse model based on carotid calcification this study characterized mechanisms that could contribute to brain d...

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Detalles Bibliográficos
Autores principales: Muhire, Gervais, Iulita, M. Florencia, Vallerand, Diane, Youwakim, Jessica, Gratuze, Maud, Petry, Franck R., Planel, Emmanuel, Ferland, Guylaine, Girouard, Hélène
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6512142/
https://www.ncbi.nlm.nih.gov/pubmed/31057061
http://dx.doi.org/10.1161/JAHA.118.011630