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Fine-particulate matter aggravates cigarette smoke extract–induced airway inflammation via Wnt5a–ERK pathway in COPD
BACKGROUND: Exposure to environmental particulate matter (PM) ≤2.5 μm in diameter (PM(2.5)) and smoking are common contributors to COPD, and pertinent research implicates both factors in pulmonary inflammation. Using in vivo mouse and in vitro human cellular models, we investigated the joint impact...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6512785/ https://www.ncbi.nlm.nih.gov/pubmed/31190784 http://dx.doi.org/10.2147/COPD.S195794 |