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Fine-particulate matter aggravates cigarette smoke extract–induced airway inflammation via Wnt5a–ERK pathway in COPD

BACKGROUND: Exposure to environmental particulate matter (PM) ≤2.5 μm in diameter (PM(2.5)) and smoking are common contributors to COPD, and pertinent research implicates both factors in pulmonary inflammation. Using in vivo mouse and in vitro human cellular models, we investigated the joint impact...

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Detalles Bibliográficos
Autores principales:	Wang, Zhihua, Zhao, Junling, Wang, Ting, Du, Xiaohui, Xie, Jungang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6512785/ https://www.ncbi.nlm.nih.gov/pubmed/31190784 http://dx.doi.org/10.2147/COPD.S195794

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