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Acute myeloid leukemia patient with FLT3-ITD and NPM1 double mutation should undergo allogeneic hematopoietic stem cell transplantation in CR1 for better prognosis
Background: According to the recent National Comprehensive Cancer Network (NCCN) guidelines, the risk level in acute myeloid leukemia (AML) patients with FLT3-ITD and NPM1 double mutation (AML(FLT3-ITD+/NPM1+)) depends on the allelic ratio of FLT3-ITD. But despite a low or high allelic ratio of FLT3...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6512860/ https://www.ncbi.nlm.nih.gov/pubmed/31190985 http://dx.doi.org/10.2147/CMAR.S194523 |