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Acute myeloid leukemia patient with FLT3-ITD and NPM1 double mutation should undergo allogeneic hematopoietic stem cell transplantation in CR1 for better prognosis 

Background: According to the recent National Comprehensive Cancer Network (NCCN) guidelines, the risk level in acute myeloid leukemia (AML) patients with FLT3-ITD and NPM1 double mutation (AML(FLT3-ITD+/NPM1+)) depends on the allelic ratio of FLT3-ITD. But despite a low or high allelic ratio of FLT3...

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Detalles Bibliográficos
Autores principales: Huang, Yan, Hu, Juan, Lu, Ting, Luo, Yi, Shi, Jimin, Wu, Wenjun, Han, Xiaoyan, Zheng, Weiyan, He, Jingsong, Cai, Zhen, Wei, Guoqing, Huang, He, Sun, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6512860/
https://www.ncbi.nlm.nih.gov/pubmed/31190985
http://dx.doi.org/10.2147/CMAR.S194523