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Connect-four: genomic analyses of regenerating stem cells identifies zygotic Dux factors as tumor initiators

How, if and in which cell types embryonic gene expression programs are elicited to induce tumor formation remains poorly understood. Through genomic analyses of regenerating, p53 deficient muscle stem cells we identified various oncogenomic amplifications, including but not limited to, the zygotic t...

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Detalles Bibliográficos
Autores principales: Preussner, Jens, Zhong, Jiasheng, Looso, Mario, Braun, Thomas, Kim, Johnny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6512926/
https://www.ncbi.nlm.nih.gov/pubmed/31131298
http://dx.doi.org/10.1080/23723556.2019.1565469