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Dilute-and-shoot analysis of therapeutic monoclonal antibody variants in fermentation broth: a method capability study
Monoclonal antibodies (mAbs) are widely applied as highly specific and efficient therapeutic agents for various medical conditions, including cancer, inflammatory and autoimmune diseases. As protein production in cellular systems inherently generates a multitude of molecular variants, manufacturing...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6512939/ https://www.ncbi.nlm.nih.gov/pubmed/30668249 http://dx.doi.org/10.1080/19420862.2018.1563034 |