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FOXO1 transcription factor plays a key role in T cell—HIV-1 interaction

HIV-1 is dependent on the host cell for providing the metabolic resources for completion of its viral replication cycle. Thus, HIV-1 replicates efficiently only in activated CD4(+) T cells. Barriers preventing HIV-1 replication in resting CD4(+) T cells include a block that limits reverse transcript...

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Detalles Bibliográficos
Autores principales: Roux, Arthur, Leroy, Héloise, De Muylder, Bénédicte, Bracq, Lucie, Oussous, Samia, Dusanter-Fourt, Isabelle, Chougui, Ghina, Tacine, Rachida, Randriamampita, Clotilde, Desjardins, Delphine, Le Grand, Roger, Bouillaud, Frederic, Benichou, Serge, Margottin-Goguet, Florence, Cheynier, Remi, Bismuth, Georges, Mangeney, Marianne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6513100/
https://www.ncbi.nlm.nih.gov/pubmed/31042779
http://dx.doi.org/10.1371/journal.ppat.1007669