Cargando…

SCALOP: sequence-based antibody canonical loop structure annotation

MOTIVATION: Canonical forms of the antibody complementarity-determining regions (CDRs) were first described in 1987 and have been redefined on multiple occasions since. The canonical forms are often used to approximate the antibody binding site shape as they can be predicted from sequence. A rapid p...

Descripción completa

Detalles Bibliográficos
Autores principales: Wong, Wing Ki, Georges, Guy, Ros, Francesca, Kelm, Sebastian, Lewis, Alan P, Taddese, Bruck, Leem, Jinwoo, Deane, Charlotte M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6513161/
https://www.ncbi.nlm.nih.gov/pubmed/30321295
http://dx.doi.org/10.1093/bioinformatics/bty877