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Deficiency of Sphingosine-1-Phosphate Receptor 2 (S1P(2)) Attenuates Bleomycin-Induced Pulmonary Fibrosis
Sphingosine 1-phosphate (S1P) levels are often found to be elevated in serum, bronchoalveolar lavage, and lung tissue of idiopathic pulmonary fibrosis patients and experimental mouse models. Although the roles of sphingosine kinase 1 and S1P receptors have been implicated in fibrosis, the underlying...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Society of Applied Pharmacology
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6513183/ https://www.ncbi.nlm.nih.gov/pubmed/30293251 http://dx.doi.org/10.4062/biomolther.2018.131 |