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Deficiency of Sphingosine-1-Phosphate Receptor 2 (S1P(2)) Attenuates Bleomycin-Induced Pulmonary Fibrosis

Sphingosine 1-phosphate (S1P) levels are often found to be elevated in serum, bronchoalveolar lavage, and lung tissue of idiopathic pulmonary fibrosis patients and experimental mouse models. Although the roles of sphingosine kinase 1 and S1P receptors have been implicated in fibrosis, the underlying...

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Detalles Bibliográficos
Autores principales: Park, Soo-Jin, Im, Dong-Soon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6513183/
https://www.ncbi.nlm.nih.gov/pubmed/30293251
http://dx.doi.org/10.4062/biomolther.2018.131