Differential Gene Expression Common to Acquired and Intrinsic Resistance to BRAF Inhibitor Revealed by RNA-Seq Analysis

Melanoma cells have been shown to respond to BRAF inhibitors; however, intrinsic and acquired resistance limits their clinical application. In this study, we performed RNA-Seq analysis with BRAF inhibitor-sensitive (A375P) and -resistant (A375P/Mdr with acquired resistance and SK-MEL-2 with intrinsi...

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Detalles Bibliográficos
Autores principales: Ahn, Jun-Ho, Hwang, Sung-Hee, Cho, Hyun-Soo, Lee, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6513187/
https://www.ncbi.nlm.nih.gov/pubmed/30293252
http://dx.doi.org/10.4062/biomolther.2018.133

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6513187/
https://www.ncbi.nlm.nih.gov/pubmed/30293252
http://dx.doi.org/10.4062/biomolther.2018.133

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