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CXCL8((3–72)) K11R/G31P protects against sepsis-induced acute kidney injury via NF-κB and JAK2/STAT3 pathway

BACKGROUND: Acute kidney injury (AKI), which is mainly caused by sepsis, has high morbidity and mortality rates. CXCL8((3–72)) K11R/G31P (G31P) can exert therapeutic effect on inflammatory diseases and malignancies. We aimed to investigate the effect and mechanism of G31P on septic AKI. METHODS: An...

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Detalles Bibliográficos
Autores principales: Zhou, Yunfeng, Xu, Wenda, Zhu, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6513525/
https://www.ncbi.nlm.nih.gov/pubmed/31084615
http://dx.doi.org/10.1186/s40659-019-0236-5