Cargando…

The Hox transcription factor Ubx stabilizes lineage commitment by suppressing cellular plasticity in Drosophila

During development cells become restricted in their differentiation potential by repressing alternative cell fates, and the Polycomb complex plays a crucial role in this process. However, how alternative fate genes are lineage-specifically silenced is unclear. We studied Ultrabithorax (Ubx), a multi...

Descripción completa

Detalles Bibliográficos
Autores principales: Domsch, Katrin, Carnesecchi, Julie, Disela, Vanessa, Friedrich, Jana, Trost, Nils, Ermakova, Olga, Polychronidou, Maria, Lohmann, Ingrid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6513553/
https://www.ncbi.nlm.nih.gov/pubmed/31050646
http://dx.doi.org/10.7554/eLife.42675