HIV blocks Type I IFN signaling through disruption of STAT1 phosphorylation

This study investigates the modulation of Type I IFN induction of an antiviral state by HIV. IFNs, including IFN-α, are key innate immune cytokines that activate the JAK/STAT pathway leading to the expression of IFN-stimulated genes. IFN-stimulated gene expression establishes the antiviral state, li...

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Detalles Bibliográficos
Autores principales: Nguyen, Nam V, Tran, James T, Sanchez, David Jesse
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6513668/
https://www.ncbi.nlm.nih.gov/pubmed/30282499
http://dx.doi.org/10.1177/1753425918803674

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6513668/
https://www.ncbi.nlm.nih.gov/pubmed/30282499
http://dx.doi.org/10.1177/1753425918803674

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