In vivo safety profile and biodistribution of GMP-manufactured human skin-derived ABCB5-positive mesenchymal stromal cells for use in clinical trials

BACKGROUND AIMS. Human dermal ABCB5-expressing mesenchymal stromal cells (ABCB5(+) MSCs) represent a promising candidate for stem cell based therapy of various currently uncurable diseases in several fields of regenerative medicine. We have developed and validated a method to isolate, from human ski...

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Detalles Bibliográficos
Autores principales: TAPPENBECK, NILS, SCHRÖDER, HANNES M., NIEBERGALL-ROTH, ELKE, HASSINGER, FATHEMA, DEHIO, ULF, DIETER, KATHRIN, KRAFT, KORINNA, KERSTAN, ANDREAS, ESTERLECHNER, JASMINA, FRANK, NATASHA Y., SCHARFFETTER-KOCHANEK, KARIN, MURPHY, GEORGE F., ORGILL, DENNIS P., BECK, JOACHIM, FRANK, MARKUS H., GANSS, CHRISTOPH, KLUTH, MARK A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6513723/
https://www.ncbi.nlm.nih.gov/pubmed/30878384
http://dx.doi.org/10.1016/j.jcyt.2018.12.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6513723/
https://www.ncbi.nlm.nih.gov/pubmed/30878384
http://dx.doi.org/10.1016/j.jcyt.2018.12.005

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