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Alisol B 23-acetate-induced HepG2 hepatoma cell death through mTOR signaling-initiated G(1) cell cycle arrest and apoptosis: A quantitative proteomic study
OBJECTIVE: The present study aimed to investigate the molecular events in alisol B 23-acetate (ABA) cytotoxic activity against a liver cancer cell line. METHODS: First, we employed a quantitative proteomics approach based on stable isotope labeling by amino acids in cell culture (SILAC) to identify...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6513739/ https://www.ncbi.nlm.nih.gov/pubmed/31156308 http://dx.doi.org/10.21147/j.issn.1000-9604.2019.02.12 |