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Alisol B 23-acetate-induced HepG2 hepatoma cell death through mTOR signaling-initiated G(1) cell cycle arrest and apoptosis: A quantitative proteomic study

OBJECTIVE: The present study aimed to investigate the molecular events in alisol B 23-acetate (ABA) cytotoxic activity against a liver cancer cell line. METHODS: First, we employed a quantitative proteomics approach based on stable isotope labeling by amino acids in cell culture (SILAC) to identify...

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Detalles Bibliográficos
Autores principales: Xia, Ji, Luo, Qiang, Huang, Shengbin, Jiang, Fuquan, Wang, Lin, Wang, Guanghui, Xie, Jingjing, Liu, Jie, Xu, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6513739/
https://www.ncbi.nlm.nih.gov/pubmed/31156308
http://dx.doi.org/10.21147/j.issn.1000-9604.2019.02.12