MAVS polymers smaller than 80 nm induce mitochondrial membrane remodeling and interferon signaling

Double‐stranded RNA (dsRNA) is a potent proinflammatory signature of viral infection and is sensed primarily by RIG‐I‐like receptors (RLRs). Oligomerization of RLRs following binding to cytosolic dsRNA activates and nucleates self‐assembly of the mitochondrial antiviral‐signaling protein (MAVS). In...

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Detalles Bibliográficos
Autores principales: Hwang, Ming‐Shih, Boulanger, Jérôme, Howe, Jonathan D., Albecka, Anna, Pasche, Mathias, Mureşan, Leila, Modis, Yorgo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6513760/
https://www.ncbi.nlm.nih.gov/pubmed/30715798
http://dx.doi.org/10.1111/febs.14772

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6513760/
https://www.ncbi.nlm.nih.gov/pubmed/30715798
http://dx.doi.org/10.1111/febs.14772

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